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Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science

Observe: This text was the MASS Analysis Evaluation cowl story for July 2023 and is a evaluate of a current paper by Van Vossel et al. If you’d like extra content material like this, subscribe to MASS.

Key Factors

  1. Researchers categorised 95 novice trainees (38 girls and 57 males) as having sluggish or quick twitch muscle fiber typology primarily based on intramuscular carnosine ranges. They examined the connection between fiber typology and reps to failure on the leg extension, leg curl, biceps curl, and triceps extension workouts at a mixture of relative intensities starting from 40-80%.
  2. Topics categorised as quick twitch people carried out considerably fewer reps to failure on the leg extension, leg curl, and biceps curl than sluggish twitch-classified people. Nevertheless, the variety of reps carried out on the triceps extension was not considerably associated to fiber typology.
  3. The presently reviewed examine means that people with a better proportion of sort II fibers are inclined to carry out fewer reps to failure on sure workouts. Nevertheless, the correlations reported on this examine weren’t very sturdy (all r ≤ 0.42); thus, it might be a stretch to say that reps to failure can predict fiber typology with excessive accuracy. 

Whereas some extent of scientific assist might be discovered at instances that one coaching type is superior to a different, we additionally perceive that charges of hypertrophy and energy acquire are extremely particular person (2, 3, 4, 5). We can also say that, on common, people might carry out about 10 reps to failure with a load comparable to 75% of 1RM on the squat or bench press. Nevertheless, substantial interindividual variation in reps carried out at a given relative depth (proportion of 1RM) exists. For instance, current knowledge point out that educated women and men carried out a variety of 6 – 28 repetitions on a squat set to failure at 70% of 1RM (6).

That particular person variation sparks, what I imagine, is essentially the most urgent coaching query we face in the present day: why does this particular person variation exist? Relating to repetition efficiency, knowledge have proven (6) that a person’s physique mass explains 20% of the variance in reps carried out to failure at a given relative depth, with heavier people finishing fewer reps to failure. Nevertheless, that leaves 80% of the variance unexplained. One standard suggestion to elucidate the remaining variance is that people with the next proportion of sort I fibers (sluggish twitch) have higher muscular endurance than these with sort II fibers. This suggestion is smart, as sort I fibers are extra proof against fatigue than sort II fibers. A earlier foray into this matter (7 – MASS Evaluation) discovered that amongst 30 men and women, these with extra sort II fibers tended to carry out fewer squat reps to failure at 80% of 1RM, however the correlation wasn’t that sturdy (rho = –0.38), leaving the conclusions tenuous. Fortunately, a brand new examine from Van Vossel et al. (1) investigated the connection between muscle typology and repetition efficiency at varied relative intensities amongst 95 men and women.

Objective and Hypotheses

Objective

The reviewed examine had three particular goals:

  1. To find out if maximal dynamic energy and isometric energy differed between people categorised into sluggish and quick typologies.
  2. To look at the connection between muscle typology and reps carried out to failure on leg extensions, leg curls, biceps curls, and triceps extensions.
  3. To look at if varied elements (relative depth and energy stage) influenced the variety of reps to failure. 

Hypotheses  

The researchers hypothesized that people with a sooner muscle typology (a better proportion of sort II fibers) would have better max energy and carry out fewer reps on varied workouts (leg extension, leg curl, biceps curl, and triceps extension). 

Topics and Strategies

Topics

Ninety 5 girls (n = 38) and males (n = 57) participated within the examine. The researchers described the topics as “resistance coaching novices who had by no means participated in a structured resistance coaching program.” Further topic traits might be seen in Desk 1.

0723 Zourdos Groups Table1
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 58

Pre-Testing for All Topics

Earlier than splitting topics into teams, the researchers wanted to find out muscle fiber typology. They did this through magnetic resonance spectroscopy, which identifies the chemical make-up of scanned tissue. On this case, the researchers examined the quantity of carnosine within the scanned muscle. As it’s possible you’ll recall, carnosine is a dipeptide of which beta-alanine is the rate-limiting precursor (i.e., to extend muscle carnosine successfully, it is best to take beta-alanine moderately than carnosine itself). Along with serving as a physiological buffer to delay fatigue, naturally occurring carnosine additionally signifies muscle fiber sort. Particularly, increased quantities of carnosine are related to extra quick twitch (sort II) fibers, whereas decrease quantities of carnosine are related to having extra sluggish twitch (sort I) fibers. With out moving into pointless specifics of the methodology, the researchers assessed fiber sort by means of this system for the vastus lateralis, gastrocnemius, and soleus after which estimated biceps, triceps, and hamstring typology from these muscular tissues. As soon as fiber sort was established, the researchers transformed carnosine content material to a z-score (extra on this within the Criticisms and Statistical Musings part), and topics had been categorised as quick twitch, intermediate twitch, or sluggish twitch. The researchers then assessed 1RM isometric leg extension torque for all topics.

After these preliminary assessments for all 95 topics, the researchers cut up the topics into two teams to reply completely different analysis questions. One of many teams (the repetition group) contained a subgroup. Determine 1 supplies a breakdown of group and subgroup construction; then, the next sections clarify the particular procedures.

0723 Zourdos Groups Fig1
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 59

Repetition Group

Along with testing leg extension isometric torque, all topics within the repetition group additionally examined their dynamic 1RM on leg extensions, biceps curls, triceps extensions, and leg curls. Subsequent, all people within the repetition group carried out three units to failure on leg extensions and biceps curls at 60% of 1RM. The train subgroup then carried out extra units to failure (the researchers didn’t specify what number of) at 60% of 1RM on the identical day, whereas the load subgroup carried out three extra units to failure at 80% of 1RM and extra units to failure at 40% of 1RM over two extra days.

Carnosine Group

One other 43 topics, the carnosine group, carried out solely three units to failure on leg extensions and curls following the preliminary assessments, however didn’t carry out any dynamic 1RM testing. 

Strategies Abstract and Outcomes

For readability, Desk 2 conveys every process carried out by every group or subgroup, and Desk 3 lists the result measures assessed in every group or subgroup. One other observe is that the researchers examined if higher leg fat-free mass (estimated from a scale), energy stage, or physique mass influenced the variety of reps carried out to failure.

0723 Zourdos Groups Table2
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 60
0723 Zourdos Groups Table3
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 61

Findings

The principle take residence of the findings is that people categorised as having quick twitch muscle fiber typology tended to carry out fewer reps throughout units to failure on the leg extension, leg curl, and biceps curls than people categorised as having sluggish twitch fiber typology. Muscle fiber typology didn’t considerably affect reps carried out on the triceps extension. Additional particulars for all consequence measures are within the following subsections.

Relationship Between Typology and Isometric Power

Throughout all topics, there was a major relationship between carnosine z-score and leg extension isometric torque (r = 0.30, p = 0.003) and relative torque (r = 0.22, p = 0.03), indicating that quick typology people may generate extra drive (i.e., had been stronger). When damaged down by intercourse, solely males exhibited vital relationships between z-scores with each absolute (males: r = 0.37, p= 0.01; girls: r = 0.19, p = 0.24) and relative (males: r = 0.26, p = 0.05; girls: r = 0.16; p = 0.35) leg extension torque.

Relationship Between Typology and Reps Carried out

Leg Extension and Leg Curls

Quick twitch people carried out considerably fewer reps to failure than sluggish twitch people at 60% of 1RM on each the leg extension (p = 0.03) and leg curl (p = 0.01) (Determine 2). Additional, there was a major inverse relationship between carnosine z-score and reps carried out to failure on leg extensions and leg curls (r = –0.44; p = 0.003), indicating that quick twitch typology people tended to carry out fewer reps than sluggish twitch people. These findings weren’t considerably impacted by any covariate (higher leg fat-free mass, energy, or physique mass). There was additionally no vital interplay by set, that means that the speed of fatigue (lower in reps carried out from set to set) was not considerably completely different between quick and slow-twitch people. Nevertheless, coaching load (40, 60, or 80% of 1RM) did impression reps carried out within the load subgroup. Particularly, there have been vital inverse relationships between carnosine z-score and reps carried out at 60% (r = –0.41, p = 0.05) and 80% (r = –0.42, p = 0.04) of 1RM, however not at 40% (r = –0.23, p = 0.28). These findings point out that quick twitch people tended to carry out fewer reps than sluggish twitch people at 60 and 80% of 1RM however not at 40% of 1RM.

0723 Zourdos Groups Fig2
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 62

Biceps Curls and Triceps Extensions

Quick twitch people carried out considerably fewer reps to failure at 60% of 1RM on the biceps curl (p = 0.02); nonetheless, there was no vital distinction between teams for reps carried out on the triceps extension (p = 0.96). Additional, reps carried out on both train weren’t considerably influenced by energy stage or physique mass (p > 0.05).

0723 Zourdos Groups Fig3
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 63

Variance in Reps Carried out

Lastly, I wish to spotlight the vary of reps carried out, which was huge. For instance, throughout three units of the biceps curl at 60% of 1RM, a variety of 18 – 62 reps was accomplished. The vary of reps carried out for all workouts with all three units mixed is in Desk 4.

0723 Zourdos Groups Table4
Muscle Fiber Composition is Associated to Repetition Efficiency In Some Muscle Teams • Stronger by Science 64

Criticisms and Statistical Musings

Whereas not a criticism per se, this part explains the strategies for these wanting a extra full understanding of how this examine’s outcomes had been derived. A crucial piece of the evaluation within the presently reviewed examine was classifying topics as quick, sluggish, or intermediate twitch. To make this classification, a standardized “rating” wanted to be created to check people to a reference worth. On this examine, the researchers had carnosine concentrations already established for a management inhabitants consisting of “energetic, wholesome non-athlete” people for the gastrocnemius and soleus (girls = 112; males = 163) and the vastus lateralis (girls = 56; males = 70). Subsequently, to categorise people into excessive, intermediate, or sluggish twitch muscle fiber typologies, the researchers created a z-score for every particular person’s carnosine focus and in contrast that rating to the imply rating of the management dataset. A z-score is a standardized rating that signifies the magnitude of normal deviations the metric differs from the imply of your entire dataset. On this examine, the z-score was calculated as z = (noticed worth) – (imply of the management knowledge set) / customary deviation of the management knowledge set. People had been categorised as sluggish twitch if they’d a z-score of ≤ -0.5, intermediate twitch with a z-score between -0.5 to +0.5, and quick twitch with a z-score of ≥5.

Interpretation

As said on this article’s introduction, I imagine essentially the most crucial questions in up to date coaching analysis are associated to figuring out the elements that specify inter-individual variations in coaching responses. For instance, the speed of hypertrophy and energy is very variable (2, 3, 4, 5); some people develop extra with drop units and a few with conventional units (6), and the variety of reps carried out to failure at a given relative depth can be extremely variable (6, 9, 10). But, we all know little or no about why the interindividual variance is so nice. Within the mid to late 2000s, knowledge revealed that these with extra satellite tv for pc cells and myonuclei per myofiber tended to expertise extra muscle progress (5). Extra lately, researchers noticed that people who grew extra and gained extra energy in response to increased quantity coaching additionally tended to have better ranges of ribosomal biogenesis (i.e., will increase in muscle ribosome content material) (11). Nevertheless, none of these findings are sensible for the coach and lifter. In follow, coaches and lifters have to make use of trial and error to find out what coaching type somebody responds greatest to. Subsequently, analysis should try to look at sensible methods to elucidate particular person variation.

Why Have a Sensible Fiber Typology Evaluation?

So, what’s sensible about assessing fiber typology by means of an imaging approach? Effectively, nothing immediately. Nevertheless, if fiber typology can predict reps to failure, somebody may do a set to failure and decide whether or not they’re primarily quick or sluggish twitch. The subsequent query is, why does figuring out if somebody is a quick or sluggish twitch particular person matter? Effectively, there is a few proof that having this data may impression programming selections. For instance, other than realizing if a lifter has good muscular endurance, one examine (12 – MASS Evaluation) confirmed that people with the next proportion of sort II fibers took longer to get better from a maximal bout of biking than these with sort I fibers. The elongated restoration time may have an effect on coaching frequency and coaching quantity; thus, figuring out fiber sort classification may enable a lifter to handle their quantity per session accordingly to make sure applicable restoration. Different examples embody the likelihood that people categorised as quick twitch could also be extra liable to overreaching (13 – MASS Evaluation) and that low-load blood-flow restriction coaching might preferentially trigger hypertrophy of sort I fibers. I’m unsure any of the above examples are definitive. Nevertheless, there’s sufficient analysis to counsel the likelihood {that a} easy rep take a look at to find out fiber typology could possibly be sensible and helpful. 

The Findings from Van Vossel et al. (1)

The presently reviewed examine from Van Vossel et al (1) discovered that quick twitch people tended to carry out fewer reps to failure at 60% of 1RM on the leg extension, leg curl, and biceps curl however not on the triceps extension than sluggish twitch people. Moreover, quick twitch people additionally carried out considerably fewer reps to failure than sluggish twitch people at 80% of 1RM on the leg extension and leg curl; nonetheless, fiber typology didn’t considerably affect reps to failure at 40% of 1RM. There are two methods to interpret this knowledge. On the one hand, somebody may level to the considerably tenuous relationships between fiber typology with leg extension (r = –0.41) and leg curl (r = –0.42) at 60% of 1RM and say that the r2-value was solely about 0.20, which suggests fiber typology solely explains 20% of the variance in reps carried out. Somebody may additionally say that the p-values for the connection between typology and reps carried out at 60% (p = 0.05) and 80% (p = 0.04) of 1RM on the leg extension and leg curl barely crossed the importance threshold. Moreover, Corridor et al (7 – MASS Evaluation) additionally reported correlations (Spearman correlations versus Pearson) (rho = –0.38; p = 0.039) that hardly crossed the importance threshold exhibiting a better proportion of sort II fibers to be associated to fewer reps to failure at 80% of 1RM on the squat in educated men and women. Furthermore, one other examine from Douris et al (14) discovered that when fiber typology was estimated from a 55-rep fatigue take a look at on a dynamometer, there was a major relationship between reps carried out and leg extension reps to failure at 70% of 1RM (r = –0.48; p = 0.02). Lastly, Terzis et al (15) discovered that energetic males with a sluggish twitch typology (fiber sort composition >50%) carried out just one extra rep to failure, on common, on the leg press in comparison with quick twitch people, which was not a statistically vital distinction. In different phrases, all of those findings barely cross the importance threshold, and one may conclude that these knowledge aren’t stable sufficient to conclude that rep exams can be utilized to foretell fiber typology. 

However, somebody may level to all of the aforementioned research (1, 7, 14, 15) and conclude that though the relationships aren’t significantly sturdy, they present a transparent development. The authors of the presently reviewed examine, Corridor et al (7) and Douris et al (14) all noticed vital correlations exhibiting that sluggish twitch-classified people carried out extra reps to failure at relative intensities between 60 – 80% of 1RM. Moreover, one may argue that despite the fact that the findings from Terzis et al weren’t vital, the yet another rep, on common, in favor of sluggish twitch people follows the development of the opposite research. Additional, Terzis et al (15) did discover a vital relationship, and a reasonably sturdy one (r = 0.70; p = 0.01) between capillaries per mm2 of muscle cross-sectional space, in any other case often called ‘capillary density” and reps to failure at 70% of 1RM on the leg press. An optimist would say that discovering is essential as a result of sort I fibers sometimes have way more capillaries than sort II fibers (16), and capillaries have many mitochondria, cardio enzymes, and plenty of myoglobin (offering extra oxygen to the muscular tissues), which all assist sort I fibers’ fatigue resistance. 

Though I’m cautiously optimistic, I take extra of the latter view on this matter as I feel these research present a transparent development. I don’t suppose the info are sturdy sufficient to make all out predictions; nonetheless, if somebody performs nicely above the imply (e.g., two customary deviations) for reps to failure, there may be actually sufficient knowledge to counsel that their fiber typology might have one thing to do with it. Nevertheless, the info should not sturdy sufficient to make particular claims corresponding to “each rep above the imply is related to 1% extra sort I fiber composition.” That sort of declare would require a way more exact take a look at with stronger correlations, and thus can be fully inappropriate. My recommendation is to take this knowledge for what it’s price – there’s in all probability one thing there, nevertheless it’s not but definitive sufficient to drive coaching selections.

It’s additionally price noting that Van Vossel et al (1) didn’t discover that sluggish twitch people carried out extra reps than quick twitch people on the mendacity triceps extension. The authors argue that one clarification for that is that the triceps are overwhelmingly composed of quick twitch fibers. Additional, since researchers estimated triceps fiber typology from different muscular tissues, it’s seemingly that triceps composition was completely different from different muscular tissues and that every one topics had quick twitch dominant triceps. However, the gastrocnemius is a few 50/50 cut up between quick twitch and sluggish twitch, on common. Though the vastus lateralis tends to have extra quick twitch muscle fibers, researchers have reported a big variation 13 – 18% for fiber sort composition of the vastus lateralis. Subsequently, reps to failure on some workouts could also be affected by fiber typology greater than others. 

Moderators of Rep Efficiency and Common Variance in Reps Carried out

Within the presently reviewed examine, fiber typology accounts for roughly 20% of the variance in rep efficiency on the leg extension and leg curl, which suggests 80% of the variance was unexplained. Curiously, the moderator’s intercourse, absolute energy, relative energy, and higher leg fat-free mass didn’t considerably have an effect on reps to failure. The issue that moderated the connection between typology and reps to failure was relative depth (load lifted). Particularly, typology was associated to reps carried out at 60% and 80% of 1RM however not at 40% of 1RM.

Analysis failing to determine predictors of reps carried out is fascinating, contemplating the big interindividual variation. For instance, Desk 4 within the Findings sections illustrates that over three units to failure on the leg curl, the vary of reps carried out was 71 – 344 (40% of 1RM), 26 – 75 (60% of 1RM), and 14 – 33 reps (80% of 1RM). This phenomenon is current in lots of workouts, as proven in a foundational examine from Hoeger et al (9) in each educated and untrained men and women, in a examine in each resistance-trained and endurance-trained people from Richens and Cleather (10), and from Cooke et al (6) in a examine on educated men and women. Cooke et al (6) not solely discovered that educated men and women carried out a variety of 6 – 28 squat reps at 70% 1RM, however additionally they present in a a number of regression analyzing elements (physique mass, body-fat %, femur size, age, and intercourse) influencing reps to failure that physique mass was virtually vital (p = 0.057). Whereas intriguing, extra analysis is required to verify the near-significant discovering that those that weigh extra are inclined to carry out fewer reps to failure. 

Further Ideas 

One side of the findings I nonetheless want to deal with is the weak however statistically vital correlation (r = 0.22; p = 0.03) between isometric leg extension peak torque and fiber typology, indicating that quick twitch people are inclined to have better isometric leg extension energy. Nevertheless, fiber typology was not associated to dynamic energy in any train. This discovering is much like Machek et al (17 – MASS Evaluation), who discovered that amongst 12 powerlifters, there was no vital relationship between sort II fibers and Wilks rating. 

Total, many different elements (e.g., leverages, muscle dimension, and many others.) affect repetition and energy functionality over simply fiber typology. Nevertheless, fiber typology impacts restoration. Subsequently, these with a better proportion of sort II fibers might want much less quantity and frequency to progress hypertrophy and energy than these with a better proportion of sort I fibers. That hypothesis is tenuous, however I deliver it as much as display the significance of figuring out elements that may affect easy methods to alter coaching variables corresponding to quantity, depth, and frequency. If analysis could make such sensible assessments, coaches and lifters can start to individualize coaching prescriptions with out present process vital trial and error.

Subsequent Steps

There are various instructions this analysis may go. One path is to recruit lifters, assess fiber typology, then observe them all around the similar coaching program and look at if typology was associated to hypertrophy and energy good points. Nevertheless, since assessing fiber sort distributions isn’t sensible, I’d prefer to see a examine that assesses varied sensible measures at baseline (reps carried out to failure, physique composition, and limb lengths, amongst different sensible metrics) and have these topics full a within-subjects design coaching examine. On this proposed examine, one limb may carry out extra steadily than the opposite. Theoretically, people who carry out fewer reps to failure throughout pre-testing would doubtlessly be quick twitch people and would wish extra restoration time and will profit from much less frequency. The identical examine is also performed however with quantity between limbs manipulated as a substitute of frequency. There are various choices for what coaching variable to control. Finally, as I mentioned on the outset of this text, the idea of individualization is essentially the most urgent query that analysis in our discipline wants to deal with, so hopefully, we see extra on this space quickly.

Software and Takeaways

  1. Van Vossel et al (1) discovered that people with a better proportion of sort II fibers tended to carry out fewer reps to failure than sluggish twitch-classified people at 60% of 1RM on the leg extension, leg curl, and biceps curl. Fiber typology didn’t affect rep efficiency on the triceps extension.
  2. Just like Van Vossel et al, different analysis has additionally reported weak however statistically vital relationships between fiber typology and rep efficiency.
  3. Regardless of the numerous relationships between fiber typology and rep efficiency, the relationships aren’t sturdy sufficient for me to advocate that coaches and lifters can definitively predict fiber sort by performing a set to failure.

This text was the quilt story for the July 2023 problem of MASS Analysis Evaluation. In the event you’d prefer to learn the total, 100-page July problem (and dive into the MASS archives), you may subscribe to MASS right here.

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References

  1. Vossel KV, Hardeel J, Van de Casteele F, de Jager S, Lievens E, Boone J, Derave W. Muscle typology influences the variety of repetitions to failure throughout resistance coaching. European Journal of Sport Science. 2023 Apr 25(just-accepted):1-21.
  2. Hubal MJ, Gordish-Dressman HE, Thompson PD, Worth TB, Hoffman EP, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF. Variability in muscle dimension and energy acquire after unilateral resistance coaching. Drugs & science in sports activities & train. 2005 Jun 1;37(6):964-72.
  3. Klemp A, Dolan C, Quiles JM, Blanco R, Zoeller RF, Graves BS, Zourdos MC. Quantity-equated high-and low-repetition every day undulating programming methods produce related hypertrophy and energy diversifications. Utilized Physiology, Diet, and Metabolism. 2016;41(7):699-705.
  4. Erskine RM, Jones DA, Williams AG, Stewart CE, Degens H. Inter-individual variability within the adaptation of human muscle particular rigidity to progressive resistance coaching. European journal of utilized physiology. 2010 Dec;110(6):1117-25.
  5. Petrella JK, Kim JS, Mayhew DL, Cross JM, Bamman MM. Potent myofiber hypertrophy throughout resistance coaching in people is related to satellite tv for pc cell-mediated myonuclear addition: a cluster evaluation. Journal of utilized physiology. 2008 Jun 1.
  6. Cooke DM, Haischer MH, Carzoli JP, Bazyler CD, Johnson TK, Varieur R, Zoeller RF, Whitehurst M, Zourdos MC. Physique mass and femur size are inversely associated to repetitions carried out within the again squat in well-trained lifters. The Journal of Power & Conditioning Analysis. 2019 Mar 1;33(3):890-5.
  7. Corridor EC, Lysenko EA, Semenova EA, Borisov OV, Andryushchenko ON, Andryushchenko LB, Vepkhvadze TF, Lednev EM, Zmijewski P, Popov DV, Generozov EV. Prediction of muscle fiber composition utilizing a number of repetition testing. Biology of Sport. 2021 Jun;38(2):277-83.
  8. Angleri V, Ugrinowitsch C, Libardi CA. Particular person Muscle Diversifications in numerous Resistance Coaching Programs in Effectively-Skilled Males. Worldwide Journal of Sports activities Drugs. 2022 Jan;43(01):55-60.
  9. Hoeger WW, Hopkins DR, Barette SL, Hale DF. Relationship between repetitions and chosen percentages of 1 repetition most: a comparability between untrained and educated men and women. The Journal of Power & Conditioning Analysis. 1990 Might 1;4(2):47-54.
  10. Richens B, Cleather DJ. The connection between the variety of repetitions carried out at given intensities is completely different in endurance and energy educated athletes. Biology of sport. 2014 Jun 1;31(2):157-61.
  11. Hammarström D, Øfsteng S, Koll L, Hanestadhaugen M, Hollan I, Apro W, Whist JE, Blomstrand E, Rønnestad BR, Ellefsen S. Advantages of upper resistance‐coaching quantity are associated to ribosome biogenesis. The Journal of physiology. 2020 Feb;598(3):543-65.
  12. Lievens E, Klass M, Bex T, Derave W. Muscle fiber typology considerably influences time to get better from high-intensity train. Journal of utilized physiology. 2020 Mar 1;128(3):648-59.
  13. Bellinger P, Desbrow B, Derave W, Lievens E, Irwin C, Sabapathy S, Kennedy B, Craven J, Pennell E, Rice H, Minahan C. Muscle fiber typology is related to the incidence of overreaching in response to overload coaching. Journal of Utilized Physiology. 2020 Oct 1;129(4):823-36.
  14. Douris PC, White BP, Cullen RR, Keltz WE, Meli J, Mondiello DM, Wenger D. The connection between maximal repetition efficiency and muscle fiber sort as estimated by noninvasive approach within the quadriceps of untrained girls. The Journal of Power & Conditioning Analysis. 2006 Aug 1;20(3):699-703.
  15. Terzis G, Spengos Ok, Manta P, Sarris N, Georgiadis G. Fiber sort composition and capillary density in relation to submaximal variety of repetitions in resistance train. The Journal of Power & Conditioning Analysis. 2008 Might 1;22(3):845-50.
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